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Psychosis Triage Protocol

A safety-first framework for deciding between the emergency department and Coordinated Specialty Care when someone presents with delusions or auditory hallucinations. Screen danger and organic instability first.

Interactive clinical tool

Clinical decision pathway simulator

Evaluate presentations through sequential assessment nodes. Follow the visual tree, or run a real-time triage calculation alongside it.

Patient presenting with delusions or auditory hallucinations
Node 1Safety priority

Imminent safety risk?

Suicidal or homicidal ideation with plan, severe aggression, command hallucinations directing harm, unable or unwilling to engage safely in care.

YES → Emergency department NOW (EMS/police if needed)NO → proceed to Node 2
Node 2Medical stability

Acute medical instability or organic cause?

Altered level of consciousness, abnormal vitals, focal neurologic signs, acute intoxication or withdrawal, delirium, rapid-onset psychosis.

YES → Emergency department (medical workup first)NO → proceed to Node 3
Node 3Functional disorganization

Gross disorganization or catatonia?

Catatonia, grossly disorganized speech or behavior, inability to meet basic needs, severe self-neglect, total ADL failure.

YES → Emergency department (inpatient stabilization)NO → proceed to Node 4
Node 4Specialized eligibility

Meets CSC program criteria?

Age 16 to 30, non-affective psychosis with onset under 2 years, no primary substance-induced, affective, organic, or ASD/ID exclusion.

YES → Refer to Coordinated Specialty CareNO → general mental health care

Triage calculator

Answer sequentially. The first "yes" determines disposition.

Calculated disposition

Refer to general mental health care

Patient is stable without acute red flags but does not meet CSC inclusion criteria (outside age 16 to 30, primary mood disorder with psychosis, affective psychosis, ASD/ID).

Action: refer to a general outpatient adolescent or adult mental health clinic.

Structured protocol

Triage decision matrix

Assess sequentially from Step 1 through Step 4. The first "yes" triggers immediate clinical disposition.

StepAssessment nodeClinical indicators (if yes)Disposition actionIf no
Step 1Imminent safety risk?
  • Suicidal / homicidal ideation with plan or intent
  • Violent behavior or aggression
  • Command hallucinations directing harm
  • Unsafe or unwilling to engage in care
Emergency department NOW

Arrange safe transport (EMS/police if necessary). Send referral documents and respect state involuntary-hold law.

Proceed to Step 2
Step 2Acute medical instability?
  • Altered level of consciousness or disorientation
  • Abnormal vitals or focal neurologic signs
  • Acute intoxication or withdrawal
  • New or rapid-onset psychosis (organic etiology)
Emergency department

Comprehensive medical evaluation (toxicology, laboratory workup) before psychiatric disposition.

Proceed to Step 3
Step 3Gross disorganization?
  • Catatonia or grossly disorganized speech/behavior
  • Serious self-neglect (not eating, drinking, sleeping)
  • Total inability to perform ADLs or complete isolation
Emergency department

Requires inpatient psychiatric hospitalization or acute stabilization.

Proceed to Step 4
Step 4Meets CSC criteria?
  • Age 16 to 30 years
  • Non-affective psychosis, onset under 2 years
  • No exclusion: primary substance-induced, mood disorder with psychosis, organic cause, ASD/ID
Refer to Coordinated Specialty Care

Preferred pathway for stable early psychosis. Multidisciplinary evidence-based care.

Refer to general mental health care

Data and outcomes

Clinical evidence and impact

Psychiatric hospitalization trajectory

CSC rapidly reduces acute re-hospitalization from roughly 70% to 10% by month 3 and holds relapse low through 24 months compared with standard care.

CSC multidisciplinary framework

Comprehensive CSC models combine six specialized domains into a unified team treatment plan for young adults with early psychosis.

Estimated initial triage breakdown

Distribution of clinical outcomes among people presenting with new-onset psychotic symptoms across emergency and outpatient screening settings.

Impact of DUP on functional recovery

Shorter duration of untreated psychosis markedly improves one-year functional recovery, which is why non-ED triage to CSC should be immediate once safety is cleared.

Key clinical caveats and legal considerations

Red flags override

A single red flag in Nodes 1 to 3 immediately overrides outpatient referral. Transport to the emergency department for safety and medical clearance before behavioral disposition.

Sequential care

The emergency department and CSC are complementary, not mutually exclusive. Patients stabilized in the ED for an acute crisis must still be referred onward to CSC when criteria are met.

Minimize DUP

Avoid unnecessary administrative delays once safety is cleared. Rapid CSC connection reduces relapse, improves long-term vocational outcomes, and saves lives.

Law and privacy

Confidentiality may be breached under state law when imminent danger to self or others, or severe functional disorganization, exists. Document thoroughly.

Primary clinical guidelines and evidence base

  1. [1]VA/DoD Clinical Practice Guideline for the Management of First-Episode Psychosis and Schizophrenia (2023). Department of Veterans Affairs.
  2. [2]Hua LL, AAP Committee on Adolescence. Collaborative Care in the Identification and Management of Psychosis in Adolescents and Young Adults. Pediatrics. 2021;147(6):e2021051486.
  3. [3]van der Ven E, et al. An Intersectional Approach to Ethnoracial Disparities in Pathways to Care Among Individuals With Psychosis in CSC. JAMA Psychiatry. 2022;79(8):790-798.
  4. [4]Nossel I, Wall MM, Scodes J, et al. Results of a Coordinated Specialty Care Program for Early Psychosis and Predictors of Outcomes. Psychiatric Services. 2018;69(8):863-870.
  5. [5]Basaraba CN, et al. Prediction Tool for Individual Outcome Trajectories Across the Next Year in First-Episode Psychosis in CSC. JAMA Psychiatry. 2023;80(1):49-56.
  6. [6]Puntis S, et al. Specialised Early Intervention Teams for Recent-Onset Psychosis. Cochrane Database of Systematic Reviews. 2020;11:CD013288.

This page was medically reviewed by Eric Wexler M.D., Ph.D. on August 14, 2026.