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CLINICAL FRAMEWORK
Neuropsychological Evaluation of Prodromal & First-Episode Psychosis
An interactive guide to the MATRICS Consensus Cognitive Battery (MCCB), critical assessment voids, social cognition profiling, neuroeconomic risk tools, and a dynamic supplemental battery builder for early psychosis.
Standardized Battery
The MCCB Benchmark
The MATRICS Consensus Cognitive Battery (MCCB) is the FDA-recognized gold standard for quantifying Cognitive Impairment Associated with Schizophrenia (CIAS). It maps seven factor-analyzed domains structurally impaired in first-episode psychosis.
MCCB Cognitive Domain Profile
Typical FEP T-Score deficit profile vs. healthy benchmark (Mean T = 50, SD = 10)
Clinical Takeaway: Speed of processing and working memory exhibit the most severe primary drops in early psychosis, serving as foundational bottlenecks for higher-order reasoning.
Explore the 7 MATRICS Domains
Click a domain for detailsMCCB Domain: SOP
T-Score Drop: -1.8 SDSpeed of Processing
Foundational processing speed deficit that mediates impairments across higher-order cognitive domains. Persists independently of positive symptoms.
Primary Instruments:BACS Symbol Coding, Trail Making (Part A), Category Fluency
Functional Outcome Link:Directly limits real-world functional capacity and daily task completion rate.